Introduction – Company Background
GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.
With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.
With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.
From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.
At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.
By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.
Core Strengths in Insole Manufacturing
At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.
Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.
We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.
With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.
Customization & OEM/ODM Flexibility
GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.
Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.
With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.
Quality Assurance & Certifications
Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.
We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.
Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.
ESG-Oriented Sustainable Production
At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.
To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.
We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.
Let’s Build Your Next Insole Success Together
Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.
From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.
Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.
🔗 Learn more or get in touch:
🌐 Website: https://www.deryou-tw.com/
📧 Email: shela.a9119@msa.hinet.net
📘 Facebook: facebook.com/deryou.tw
📷 Instagram: instagram.com/deryou.tw
Pillow ODM design company in Taiwan
Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.
With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Orthopedic pillow OEM solutions Taiwan
Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.
We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Vietnam OEM/ODM hybrid insole services
At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Vietnam insole OEM manufacturer
📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Custom graphene foam processing factory Taiwan
Humpback whale song shares statistical structures with human language, highlighting unexpected similarities in communication across species. Credit: OperationCetaces A new study finds that humpback whale song shares statistical structures with human language, suggesting that cultural transmission plays a key role in shaping complex communication. Using methods inspired by infant speech learning, researchers identified recurring patterns in whale song, challenging assumptions about the uniqueness of human language and offering new perspectives on language evolution. Humpback whale song is a remarkable example of complex, culturally transmitted behavior. However, until now, there was little evidence to suggest it possesses a language-like structure. Human language, which is also passed down culturally, follows distinct statistical patterns in the frequency of recurring elements. In humans, these patterns facilitate learning and likely contribute to language transmission across generations. This study takes an innovative approach by applying methods inspired by how infants identify words in speech to analyze humpback whale recordings. The findings reveal that whale songs exhibit the same statistical structures present in all human languages. This discovery uncovers previously undetected patterns in whale song, highlighting a profound similarity between two otherwise unrelated species—both of whom rely on culturally transmitted communication systems. Spectrogram of whale song 2017 recording. Credit: OperationCetaces Whale song has a language-like structure Language has long been considered a uniquely human trait, with features that mark it out as distinct from the communication of all other species. However, research published in Science has uncovered the same statistical structure that is a hallmark of human language in humpback whale song. Humpback whale song is a striking example of a complex, culturally transmitted behavior, but up to now, there was little evidence it has language-like structure. Human language, which is also culturally transmitted, has recurring parts whose frequency of use follows a particular pattern. In humans, these properties help learning and may come about because they help language be passed from one generation to the next. This work innovatively applies methods inspired by how babies discover words in speech to humpback whale recordings, uncovering the same statistical structures found in all human languages. This work reveals previously undetected structure in whale song, illustrating a deep commonality between two unrelated species united by the fact that their communication systems are culturally transmitted. Humpback whale calf and mother. Credit: Marc-Quintin Led by Professor Inbal Arnon of the Hebrew University, Dr Ellen Garland of the University of St Andrews, and Professor Simon Kirby of the University of Edinburgh, in collaboration with Dr Claire Garrigue (IRD New Caledonia), Dr Jenny Allen (Griffith University), and Dr Emma Carroll (University of Auckland), this work represents a unique collaboration between linguists, developmental scientists, marine biologists, and behavioral ecologists. Humpback whale song is one of the most striking examples of a socially learned, culturally transmitted behavior in a nonhuman animal. Whale song exhibits systematic structure, however, until now, there was little evidence that this structure was like that of human language. One of the big challenges in studying non-human communication is finding out what the relevant parts of the system are. The authors’ breakthrough was to use insights from how babies discover words in speech, and apply them to eight years of humpback whale song data collected in New Caledonia. The authors found that whale song showed the same key statistical properties present in all known human languages. Implications for Language Evolution and Animal Communication They detected recurring parts whose frequency closely followed a particular skewed distribution, not previously found in any other non-human animal. This work reveals a deeply unexpected commonality between two unrelated species – humans and humpback whales – united by the fact that their communication system is culturally transmitted. This points to the crucial role of learning and transmission in the emergence of structure within such systems. Once thought of as the hallmark of human uniqueness, foundational aspects of human language may be shared across evolutionary distant species. Audio Playerhttps://scitechdaily.com/images/Whale-Song-2017-Recording.wav00:0000:0000:00Use Up/Down Arrow keys to increase or decrease volume. Dr Ellen Garland from the University of St Andrews said: “Revealing this hidden language-like structure in whale song was unexpected, but it strongly suggests this cultural behavior holds crucial insight into the evolution of complex communication across the animal kingdom.” “Whale song is not a language; it lacks semantic meaning. It may be more reminiscent of human music, which also has this statistical structure, but lacks the expressive meaning found in language.” “Whether the units we detected using the infant-inspired method are salient to the whales themselves remains an open question.” Prof Inbal Arnon from the Hebrew University said: “Using insights and methods from how babies learn language allowed us to discover previously undetected structure in whale song” “This work shows how learning and cultural transmission can shape the structure of communication systems: we may find similar statistical structure wherever complex sequential behavior is transmitted culturally.” “It raises the intriguing possibility that humpback whales, like human babies, may learn their song by tracking transitional probabilities between sound elements, and using dips in those probabilities as a cue to segment the song” Prof Simon Kirby from the University of Edinburgh said: “It suggests that our understanding of the evolution of language can benefit not only from looking at our closest primate relatives, but also at cases of convergent evolution elsewhere in nature.” “Looking beyond the way language is used to express meaning, we should consider how language is learned and transmitted culturally over multiple generations.” “These findings challenge long-held assumptions about the uniqueness of human language, uncovering deep commonalities between evolutionarily distant species.” Reference: “Whale song shows language-like statistical structure” by Inbal Arnon, Simon Kirby, Jenny A. Allen, Claire Garrigue, Emma L. Carroll and Ellen C. Garland, 6 February 2025, Science. DOI: 10.1126/science.adq7055
Ichthyosporeans Sphaeroforma arctica and Chromosphaera perkinsii undergoing mitosis, depicted as two halves of a cell, rendered in Haeckel-inspired tones and a naturalist style. Credit: Nirupa Rao New findings by EMBL researchers reveal how animals and fungi have developed distinct cell division processes to accommodate their varied life cycles. Cell division is a crucial process for all life forms, from bacteria to blue whales, enabling growth, reproduction, and the continuation of species. Despite its universal nature, the methods of cell division vary significantly across organisms. A recent study by EMBL Heidelberg’s Dey group, along with their collaborators and published in Nature, investigates the evolution of cell division methods in organisms closely related to fungi and animals. For the first time, this research demonstrates the connection between an organism’s life cycle and its cell division techniques. Despite last sharing a common ancestor over a billion years ago, animals and fungi are similar in many ways. Both belong to a broader group called ‘eukaryotes’ – organisms whose cells store their genetic material inside a closed compartment called the ‘nucleus’. The two differ, however, in how they carry out many physiological processes, including the most common type of cell division – mitosis. Most animal cells undergo ‘open’ mitosis, in which the nuclear envelope – the two-layered membrane separating the nucleus from the rest of the cell – breaks down when cell division begins. However, most fungi use a different form of cell division – called ‘closed’ mitosis – in which the nuclear envelope remains intact throughout the division process. However, very little is known about why or how these two distinct modes of cell division evolved and what factors determine which mode would be predominantly followed by a particular species. Research Collaboration and Methodology This question captured the attention of scientists in the Dey Group at EMBL Heidelberg, who investigated the evolutionary origins of the nucleus and cell division. “By studying diversity across organisms and reconstructing how things evolved, we can begin to ask if there are universal rules that underlie how such fundamental biological processes work,” said Gautam Dey, Group Leader at EMBL Heidelberg. In 2020, during the COVID-19 lockdown, an unexpected path to answering this question grew out of discussions between Dey’s group and Omaya Dudin’s team at the Swiss Federal Institute of Technology (EPFL), Lausanne. Dudin is an expert in an unusual group of marine protists – Ichthyosporea. Ichthyosporea are closely related to both fungi and animals, with different species lying closer to one or the other group on the evolutionary family tree. The Dey and Dudin groups, in collaboration with Yannick Schwab’s group at EMBL Heidelberg, decided to probe the origins of open and closed mitosis using Ichthyosporea as a model. Interestingly, the researchers found that certain species of Ichthyosporea undergo closed mitosis while others undergo open mitosis. Therefore, by comparing and contrasting their biology, they could obtain insights into how organisms adapt to and use these two cell division modes. Hiral Shah, an EIPOD fellow working across the three groups, led the study. “Having recognized very early that Ichthyosporea, with their many nuclei and key evolutionary position between animal and fungi, were well-suited for addressing this question, it was clear that this would require bringing together the cell biological and technical expertise of the Dey, Dudin, and Schwab groups, and this is exactly what the EIPOD fellowship allowed me to do,” said Shah. Upon closely probing the mechanisms of cell division in two species of Ichthyosporeans, the researchers found that one species, S. arctica, favors closed mitosis, similar to fungi. S. arctica also has a life cycle with a multinucleate stage, where many nuclei exist within the same cell – another feature shared with many fungal species as well as the embryonic stages of certain animals, such as fruit flies. Another species, C. perkinsii, turned out to be much more animal-like, relying on open mitosis. Its life cycle involves primarily mononucleate stages, where each cell has a single nucleus. Implications for Understanding Eukaryotic Cell Division “Our findings led to the key inference that the way animal cells do mitosis evolved hundreds of millions of years before animals did. The work therefore has direct implications for our general understanding of how eukaryotic cell division mechanisms evolve and diversify in the context of diverse life cycles, and provides a key piece of the animal origins puzzle,” said Dey. The study combined expertise in comparative phylogenetics, electron microscopy (from the Schwab Group and the electron microscopy core facility (EMCF) at EMBL Heidelberg), and ultrastructure expansion microscopy, a technique that involves embedding biological samples in a transparent gel and physically expanding it. Additionally, Eelco Tromer, from the University of Groningen in the Netherlands, and Iva Tolic, from the Ruđer Bošković Institute in Zagreb, Croatia, provided expertise in comparative genomics and mitotic spindle geometry and biophysics, respectively. “The first time we saw an expanded S. arctica nucleus, we knew this technique would change the way we study the cell biology of non-model organisms,” said Shah, who brought back the expansion microscopy technique to EMBL Heidelberg after a stint at the Dudin lab. Dey agrees: “A key breakthrough in this study came with our application of ultrastructure expansion microscopy (U-ExM) to the analysis of the ichthyosporean cytoskeleton. Without U-ExM, immunofluorescence and most dye labeling protocols do not work in this understudied group of marine holozoans.” This study also demonstrates the importance of going beyond traditional model organism research when trying to answer broad biological questions, and the potential insights further research on Ichthyosporean systems might reveal. “Ichthyosporean development displays remarkable diversity,” said Dudin. “On one hand, several species exhibit developmental patterns similar to those of early insect embryos, featuring multinucleated stages and synchronized cellularisation. On the other hand, C. perkinsii undergoes cleavage division, symmetry breaking, and forms multicellular colonies with distinct cell types, similar to the ‘canonical view’ of early animal embryos. This diversity not only helps in understanding the path to animals but also offers a fascinating opportunity for comparative embryology outside of animals, which is, in itself, very exciting.” The project’s inherent interdisciplinarity served not only as a good testbed for this type of collaborative research but also for the unique postdoctoral training afforded at EMBL. “Hiral’s project nicely illustrates the virtue of the EIPOD program: a truly interdisciplinary project, bundling innovative biology with advanced methods, all contributing to a truly spectacular personal development,” said Schwab. “We (as mentors) witnessed the birth of a strong scientist, and this is really rewarding!” The Dey, Dudin, and Schwab groups are currently also collaborating on the PlanExM project, part of the TREC expedition – an EMBL-led initiative to explore and sample the biodiversity along European coasts. PlanExM aims to apply expansion microscopy to study the ultrastructural diversity of marine protists directly in environmental samples. “The project grew out of the realization that U-ExM is going to be a game-changer for protistology and marine microbiology,” said Dey. With this project, as well as others currently underway, the research team hopes to shed further light on the diversity of life on Earth and the evolution of the fundamental biological processes. Reference: “Life-cycle-coupled evolution of mitosis in close relatives of animals” by Hiral Shah, Marine Olivetta, Chandni Bhickta, Paolo Ronchi, Monika Trupinić, Eelco C. Tromer, Iva M. Tolić, Yannick Schwab, Omaya Dudin and Gautam Dey, 22 May 2024, Nature. DOI: 10.1038/s41586-024-07430-z
Caulobacter crescentus is a crescent-shaped dimorphic bacterium that serves as one of the primary model organisms to study bacterial cell cycle regulation, cell differentiation, and morphogenesis. The cells were visualized using the DNA-PAINT technique, with the chromosomal DNA stained blue and the cell membranes stained red. Credit: Max Planck Institute for Terrestrial Microbiology/Hernandez-Tamayo How One Regulatory Protein Acts as a Multi-Tool of Bacterial Cell Wall Remodeling For bacterial cells to grow and divide, their cell walls need continual remodeling. This process requires a careful balance of lytic enzymes and peptidoglycan production. A team of researchers headed by Martin Thanbichler discovered that a central regulator can control completely different classes of autolysins. Since many antibiotics attack the bacterial cell wall, this discovery could pave the way for new treatment methods against bacterial infections. During evolution, cells have developed a wide range of strategies to strengthen their envelope against internal osmotic pressure, thus allowing them to grow in a variety of different environments. Most bacterial species synthesize a semi-rigid cell wall surrounding the cytoplasmic membrane, whose main component, peptidoglycan, forms a dense meshwork that encases the cell. In addition to its protective role, the cell wall also serves as a means to generate specific cell shapes, such as spheres, rods, or spirals, thus facilitating motility, surface colonization, and pathogenicity. The presence of a cell wall presents its own challenges: cells must constantly remodel it in order to grow and divide. To do this, they must very carefully make tears in the wall to allow it to expand and change, while quickly mending the gaps with new material to prevent it from collapsing. This cell wall remodeling process involves the cleavage of bonds by lytic enzymes, also known as autolysins, and the subsequent insertion of new cell wall material by peptidoglycan synthases. The activities of these two antagonistic groups of proteins must be closely coordinated to prevent weak spots in the peptidoglycan layer that lead to cell lysis and death. The research team led by Martin Thanbichler, Max Planck Fellow at the Max Planck Institute for Terrestrial Microbiology and Professor of Microbiology at the University of Marburg, has set out to unravel the composition and function of the autolytic machinery. Their studies focus on the crescent-shaped bacterium Caulobacter crescentus, which is found in freshwater environments and widely used as a model organism to study fundamental cellular processes in bacteria. According to Thanbichler, studying the function of autolysins has been a challenging task. “While we know a lot about the synthetic machinery, the autolysins proved to be a tough nut to crack.” Maria Billini, a postdoctoral researcher in Thanbichler’s team, adds: “Bacteria usually harbor many types of autolysins from different enzyme families with different targets. This means that these proteins are highly redundant, and the deletion of individual autolysin genes often has little effect on cell morphology and growth.” Versatile Regulator Analysis of potential autolysin regulators by co-immunoprecipitation screening and in vitro protein-protein interaction assays has revealed that a factor called DipM plays a pivotal role in bacterial cell wall remodeling. This key regulator, a soluble periplasmic protein, surprisingly interacts with several classes of autolysins as well as a cell division factor, showing a promiscuity that was previously unknown for this type of regulator. DipM was able to stimulate the activity of two peptidoglycan-cleaving enzymes with completely different activities and folding, making it the first identified regulator that can control two classes of autolysins. Notably, the results also indicate that DipM uses a single interface to interact with its various targets. “Disruption of DipM leads to the loss of regulation at various points of the cell wall remodeling and division process and ultimately kills the cell,” says doctoral student Adrian Izquierdo Martinez, first author of the study. “Its proper function as a coordinator of autolysin activity is thus critical for proper cell shape maintenance and cell division in C. crescentus.” The comprehensive characterization of DipM revealed a novel interaction network, including a self-reinforcing loop that connects lytic transglycosylases and possibly other autolysins to the core of the cell division apparatus of C. crescentus, and very likely also other bacteria. Thus, DipM coordinates a complex autolysin network whose topology greatly differs from that of previously studied autolysin systems. Martin Thanbichler points out: “The study of such multi-enzyme regulators, whose malfunction affects several cell wall-related processes at the same time, not only helps us to understand how the cell wall responds to changes in the cell or the environment. It can also contribute to the development of new therapeutic strategies that combat bacteria by disrupting several autolytic pathways simultaneously.” Reference: “DipM controls multiple autolysins and mediates a regulatory feedback loop promoting cell constriction in Caulobacter crescentus” by Adrian Izquierdo-Martinez, Maria Billini, Vega Miguel-Ruano, Rogelio Hernández-Tamayo, Pia Richter, Jacob Biboy, María T. Batuecas, Timo Glatter, Waldemar Vollmer, Peter L. Graumann, Juan A. Hermoso and Martin Thanbichler, 11 July 2023, Nature Communications. DOI: 10.1038/s41467-023-39783-w
DVDV1551RTWW78V
Custom foam pillow OEM in Thailand 》a trusted OEM/ODM partner across comfort-driven industriesErgonomic insole ODM support Indonesia 》dedicated to product consistency, material innovation, and fast lead timeHigh-performance insole OEM factory Taiwan 》delivering product excellence through every detail